Update 6:30

Metro News - Two firefighters are dead and at least a dozen people are injured in a huge fire in downtown Boston.

A Boston TV station reports one of the firefighters was carried out of the burning apartment building in cardiac arrest.

All available fire engines were called to the scene of the nine alarm fire.  High winds have been fanning the flames.

Original Story

Associated Press - At least three Boston firefighters have been taken to hospitals and others are still battling a nine-alarm fire at a four-story brownstone in the city's Back Bay neighborhood.

Flames and smoke poured from the roof and windows of the building near Storrow Drive and the Charles River on Wednesday afternoon.

Boston EMS spokesman Nick Martin says four people, including at least three firefighters, have been taken to hospitals. He says he does not know the extent of their injuries.

State police have closed Storrow Drive to keep access clear for firefighters and are asking people to avoid the area.

The Boston Fire Department says on Twitter that the fire started in the basement and extended up.